This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.1) Conklin, D., et al., Gene 249 (1-2), 91-98 (2000) (): ().
Immunogen
This UBQLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-576 amino acids from the C-terminal region of human UBQLN3.
Antibody is used in Western blot to detect UBQLN3 in mouse cerebellum tissue lysate.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.