VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.1) Chandra, D., (2005) J. Biol. Chem. 280 (19), 19051-19061.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VDAC2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
VDAC2 antibody can be used for detection of VDAC2 by ELISA at 1:312500. VDAC2 antibody can be used for detection of VDAC2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
VDAC2 antibody can be used for detection of VDAC2 by ELISA at 1:312500. VDAC2 antibody can be used for detection of VDAC2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store VDAC2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.