Application
Western blot analysis of lysed extracts from HT29 cells untreated or treated with SCF-1 using VEGFR2 (phospho-Tyr1059).| Product Name | VEGFR2 (phospho Tyr1059) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLK1, CD309, VEGFR, VEGFR2, AMPK1, FLK1, KDR |
| Product description | Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions1) Zeng H, et al. (2001) J Biol Chem. 276 (35): 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8): 1619-1627. |
| Immunogen | VEGFR2 (phospho-Tyr1059) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1059 (P-D-Y (p) -V-R) derived from Human VEGFR2. |
| Modification | p-Tyr1059 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KDR |
|---|---|
| Alternative Names | FLK1 CD309 VEGFR VEGFR2 AMPK1 FLK1 KDR |
| Molecular Weight(MW) | 230 kDa |
| Tissue Specificity | This antibody detects endogenous level of VEGFR2 only when phosphorylated at Tyrosine 1059. |
| Entrez Gene | 3791 |
|---|---|
| Protein Accession | NP_002244.1 |
Application
Western blot analysis of lysed extracts from HT29 cells untreated or treated with SCF-1 using VEGFR2 (phospho-Tyr1059).| Application Notes | Western Blot: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
