VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene.1) Valleix, S., et al., (2006) Invest. Ophthalmol. Vis. Sci. 47 (1), 48-54.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VSX1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
VSX1 antibody can be used for detection of VSX1 by ELISA at 1:12500. VSX1 antibody can be used for detection of VSX1 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
VSX1 antibody can be used for detection of VSX1 by ELISA at 1:12500. VSX1 antibody can be used for detection of VSX1 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store VSX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt