The WNT gene family consists of structurally related genes
which encode secreted signaling proteins. These proteins have been
implicated in oncogenesis and in several developmental processes,
including regulation of cell fate and patterning during
embryogenesis. This gene is a member of the WNT gene family. It
encodes a protein which shows 95%, 86% and 71% amino acid identity
to the mouse, zebrafish and Xenopus Wnt8B proteins, respectively.
The expression patterns of the human and mouse genes appear
identical and are restricted to the developing brain. The
chromosomal location of this gene to 10q24 suggests it as a
candidate gene for partial epilepsy.1) Katoh, M., et al. Int. J. Oncol. 30(5):1273-1277(2007)
Immunogen
This WNT8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human WNT8B.
Western Blot at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.