Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Product Name | WWTR1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | WWTR1, DKFZP586I1419, TAZ |
| Product description | TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.1) Hong, J.H., (2005) Science 309 (5737), 1074-1078. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WWTR1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WWTR1 antibody can be used for detection of WWTR1 by ELISA at 1:62500. WWTR1 antibody can be used for detection of WWTR1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | WWTR1 |
|---|---|
| Alternative Names | WWTR1 DKFZP586I1419 TAZ |
| Molecular Weight(MW) | 44 kDa |
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1201 - HeLa Cell Lysate |
|---|---|
| Application Notes | WWTR1 antibody can be used for detection of WWTR1 by ELISA at 1:62500. WWTR1 antibody can be used for detection of WWTR1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store WWTR1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
