The YWHAH gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Kilani, R.T., (2007) J. Rheumatol. 34 (8), 1650-1657.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human YWHAH.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
YWHAH antibody can be used for detection of YWHAH by ELISA at 1:1562500. YWHAH antibody can be used for detection of YWHAH by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human brain at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Brain at 0.2-1 ug/ml.
Application
Antibody used in IHC on Human Intestine.
Positive Control
1) Cat. No. 1304 - Human Liver Tissue Lysate
Application Notes
YWHAH antibody can be used for detection of YWHAH by ELISA at 1:1562500. YWHAH antibody can be used for detection of YWHAH by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store YWHAH antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.