ZBTB40 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.1) Filion GJP, Zhenilo S, Salozhin S, et al. A family of zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 2006; 26:169-81.
Immunogen
ZBTB40 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human ZBTB40. The immunogen is located within amino acids 180 - 230 of ZBTB40.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISA,IF,WB
ZBTB40 antibody can be used for detection of ZBTB40 by Western blot at 0.5 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 5 μg/mL.
ZBTB40 Antibody: ZNF923 KIAA0478 Zinc finger and BTB domain-containing protein 40
Sequence Similarities
2) Cat. No. 17-007 - Raji Cell Slide
Tissue Specificity
ZBTB40 antibody is human specific. At least two isoforms of ZBTB40 are known to exist. This antibody is predicted to not cross-react with other ZBTB protein family members.
Western blot analysis of ZBTB40 in Raji cell lysate with ZBTB40 antibody at 0.5 μg/ml in (A) the absence and (B) the presence of blocking peptide.
Application
Immunofluorescence of ZBTB40 in Raji cells with ZBTB40 antibody at 20 μg/mL.
Positive Control
1) Cat. No. 1207 - Raji Cell Lysate
Application Notes
ZBTB40 antibody can be used for detection of ZBTB40 by Western blot at 0.5 μg/mL. Antibody can also be used for immunofluorescence starting at 20 μg/mL. For immunofluorescence start at 5 μg/mL.
Additional Information
Form
Liquid
Storage Instructions
ZBTB40 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
ZBTB40 Antibody is supplied in PBS containing 0.02% sodium azide.