The protein encoded by this gene is a member of the zinc
finger family of proteins. The gene product contains C2H2-type
domains, which are the classical zinc finger domains found in
numerous nucleic acid-binding proteins. This protein functions as a
regulator of the non-canonical NF-kappaB pathway in
lymphotoxin-beta receptor signaling. Alternative splicing results
in multiple transcript variants. A read-through transcript variant
composed of ZFP91 and the downstream CNTF gene sequence has been
identified, but it is thought to be non-coding. Read-through
transcription of ZFP91 and CNTF has also been observed in mouse. A
ZFP91-related pseudogene has also been identified on chromosome 2.1) Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)
Immunogen
This ZFP91 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-245 amino acids from the Central region of human ZFP91.
Western Blot at 1:2000 dilution + HL-60 whole cell lysates Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:2000 dilution + human testis lysates Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:2000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.