Protrudin, Zinc finger FYVE domain-containing protein 27, ZFYVE27
Product description
This gene encodes a protein with several transmembrane
domains, a Rab11-binding domain and a lipid-binding FYVE finger
domain. The encoded protein appears to promote neurite formation. A
mutation in this gene has been reported to be associated with
hereditary spastic paraplegia, however the pathogenicity of the
mutation, which may simply represent a polymorphism, is unclear.1) Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)
Immunogen
This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.