Application
Western blot analysis of ZMYM3 in human brain tissue lysate with ZMYM3 antibody at 1 μg/mL.Application
Immunofluorescence of ZMYM3 in human brain tissue with ZMYM3 antibody at 20 μg/mL.| Product Name | ZMYM3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | ZMYM3 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation.1) Rosenfeld R and Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn.1993; 11:557-70. |
| Immunogen | AXIN2 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human AXIN2. The immunogen is located within amino acids 220 - 270 of ZMYM3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFWB |
| ZMYM3 antibody can be used for detection of ZMYM3 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZMYM3 |
|---|---|
| Alternative Names | ZMYM3 Antibody: MYM XFIM ZNF261 DXS6673E ZNF198L2 KIAA0385 Zinc finger MYM-type protein 3 Zinc finger protein 261 |
| Sequence Similarities | 2) Cat. No. 10-301 - Human Brain Tissue Slide |
| Tissue Specificity | At least three isoforms of ZMYM3 are known to exist; this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members. |
Application
Western blot analysis of ZMYM3 in human brain tissue lysate with ZMYM3 antibody at 1 μg/mL.
Application
Immunofluorescence of ZMYM3 in human brain tissue with ZMYM3 antibody at 20 μg/mL.| Positive Control | 1) Cat. No. 1303 - Human Brain Tissue Lysate |
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| Application Notes | ZMYM3 antibody can be used for detection of ZMYM3 by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
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| Storage Instructions | ZMYM3 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZMYM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
