Application
Immunohistochemistry of ZMYM4 in human tonsil with ZMYM4 antibody at 5 μg/mL.| Product Name | ZMYM4 Antibody |
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| Antibody Type | Primary Antibodies |
| Product description | ZMYM4 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-γ-induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.1) Rosenfeld R and Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn. 1993; 11:557-70. |
| Immunogen | ZMYM4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM4. The immunogen is located within the last 50 amino acids of ZMYM4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-P |
| ZMYM4 antibody can be used for detection of ZMYM4 by immunohistochemistry at 5 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ZMYM4 |
|---|---|
| Alternative Names | ZMYM4 Antibody: MYM CDIR ZNF262 ZNF198L3 KIAA0425 Zinc finger MYM-type protein 4 Zinc finger protein 262 |
| Molecular Weight(MW) | 167 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse: (94%) |
| Tissue Specificity | At least three isoforms of ZMYM4 are known to exist; this antibody will detect all of them. ZMYM4 antibody is predicted not to cross-react with other ZMYM family members. |
Application
Immunohistochemistry of ZMYM4 in human tonsil with ZMYM4 antibody at 5 μg/mL.| Application Notes | ZMYM4 antibody can be used for detection of ZMYM4 by immunohistochemistry at 5 μg/mL. |
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| Form | Liquid |
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| Storage Instructions | ZMYM4 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ZMYM4 Antibody is supplied in PBS containing 0.02% sodium azide. |
