| Gene Full Name |
C2orf33; Chromosome 2 open reading frame 33; DKFZp666J168; GL004; Mff; MFF_HUMAN; MGC110913; Mitochondrial fission factor; OTTHUMP00000164235; |
| Target |
Phospho-MFF (Ser172) Antibody detects endogenous levels of MFF. |
| Molecular Weight(MW) |
39KD |
| Function |
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles |
| Tissue Specificity |
Highly expressed in heart, kidney, liver, brain, muscle, and stomach. |
| Cellular Localization |
Mitochondrion outer membrane. |