Application
Fig1: Western blot analysis of D1DR expression in KNRK (A) and HeLa (B) whole cell lysates.Application
Fig2： Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islet of Langerhans.| Product Name | D(1A) dopamine recepr (DRD1) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | D(1A) dopamine receptor antibody D1A dopamine receptor antibody DADR antibody Dopamine D1 receptor antibody dopamine receptor D1 antibody DR D1 antibody DR D1A antibody DRD 1 antibody DRD 1A antibody DRD1 antibody DRD1_HUMAN antibody DRD1A antibody |
| Product description | The members of the G protein coupled receptor family are distinguished by their slow transmitting response to ligand binding. These transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. -adrenergic receptor binds to adrenaline activates adenylyl cyclase, while 2-adrenergic receptor binds to adrenaline inhibits adenylyl cyclase. The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Goat |
| Tested Applications | WBIPIFIHC-P |
| WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | D(1A) dopamine receptor antibody D1A dopamine receptor antibody DADR antibody Dopamine D1 receptor antibody dopamine receptor D1 antibody DR D1 antibody DR D1A antibody DRD 1 antibody DRD 1A antibody DRD1 antibody DRD1_HUMAN antibody DRD1A antibody |
|---|---|
| Molecular Weight(MW) | 74kDa |
| Cellular Localization | Cell membrane, Endoplasmic reticulum membrane |
| SwissProt ID | P21728 |
|---|
Application
Fig1: Western blot analysis of D1DR expression in KNRK (A) and HeLa (B) whole cell lysates.
Application
Fig2： Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islet of Langerhans.| Positive Control | Hela, KNRK, human pancreas tissue. |
|---|---|
| Application Notes | WB:1:100-1:1,000 IP:1-2 μg per 100-500 μg of total protein (1 ml of cell lysate) IF:1:50-1:500 IHC:1:50-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
