Application
Fig1: Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and cells in tubules.| Product Name | TIMP-2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CSC 21K antibody CSC-21K antibody CSC21K antibody Metalloproteinase inhibitor 2 antibody Metalloproteinase inhibitor 2 precursor antibody TIMP 2 antibody TIMP metallopeptidase inhibitor 2 antibody TIMP-2 antibody TIMP2 antibody TIMP2_HUMAN antibody Tissue Inhibitor of Metalloproteinase 2 antibody Tissue inhibitor of metalloproteinases 2 antibody |
| Product description | TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase.TIMP-1 was found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Goat |
| Tested Applications | WBIPIFIHC |
| WB:1:1,000 IP:1-2 μg per 100-500 μg of total protein IF:1:50-500 IHC:1:50-500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CSC 21K antibody CSC-21K antibody CSC21K antibody Metalloproteinase inhibitor 2 antibody Metalloproteinase inhibitor 2 precursor antibody TIMP 2 antibody TIMP metallopeptidase inhibitor 2 antibody TIMP-2 antibody TIMP2 antibody TIMP2_HUMAN antibody Tissue Inhibitor of Metalloproteinase 2 antibody Tissue inhibitor of metalloproteinases 2 antibody |
|---|---|
| Molecular Weight(MW) | 21 kDa |
| Cellular Localization | Secreted |
| SwissProt ID | P16035 |
|---|
Application
Fig1: Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and cells in tubules.| Positive Control | Human kidney tissue. |
|---|---|
| Application Notes | WB:1:1,000 IP:1-2 μg per 100-500 μg of total protein IF:1:50-500 IHC:1:50-500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
