| Product Name | WNT3A/WNT3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Int 4 antibody INT4 antibody MGC131950 antibody MGC138321 antibody MGC138323 antibody Proto-oncogene Int-4 homolog antibody Proto-oncogene Wnt-3 antibody wingless type MMTV integration site family member 3 antibody Wnt 3 proto oncogene protein antibody WNT 3 proto oncogene protein precursor antibody wnt3 antibody WNT3_HUMAN antibody |
| Product description | The Wnt gene family encodes secreted signaling molecules that bind to frizzled receptors and influence oncogenesis and developmental processes, including regulation of cell fate and patterning during embryogenesis. The Wnt family has two functional classes according to their biological activities; Wnts that signal through a Wnt-1/wingless pathway by stabilizing cytoplasmic β-catenin, and Wnts that stimulate intracellular Ca2+ release and activate two kinases, CamKII and PKC, in a G protein-dependent manner. Wnt-3 is present during development of the cerebellum and is restricted to the Purkinje cell layer in the adult. In motoneurons, Wnt-3 is a retrograde signal that controls terminal branching of muscle afferents. Human Wnt-3 is 98% homologous to mouse Wnt-3 protein and 84% homologous to human Wnt-3a protein. The human Wnt-3 gene clusters with the Wnt-15 gene at chromosome 17q21.31. |
| Immunogen | peptide |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Goat |
| Tested Applications | WBIF |
| WB:1:100-1:1,000 IF:1:50-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | Int 4 antibody
INT4 antibody MGC131950 antibody MGC138321 antibody MGC138323 antibody Proto-oncogene Int-4 homolog antibody Proto-oncogene Wnt-3 antibody wingless type MMTV integration site family member 3 antibody Wnt 3 proto oncogene protein antibody WNT 3 proto oncogene protein precursor antibody wnt3 antibody WNT3_HUMAN antibody |
|---|---|
| Molecular Weight(MW) | 39 kDa |
| Cellular Localization | Secreted |
| SwissProt ID | P56703 |
|---|
| Application Notes | WB:1:100-1:1,000 IF:1:50-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ |
| Storage Buffer | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
