WB
Western blot analysis using TGF beta1 antibody against Hela (1), A431 (2) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using TGF beta1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using TGF beta1 antibody with DAB staining.IHC
(E) At 24 h post-pneumococcal 19F infection, immunohistochemical staining with anti-TGF-β1 polyclonal antibody was utilized to detect expression of TGF-β1 in lung tissues. Lung sections were examined under light microscopy at magnification 200× (scale bar = 100 µm) and 400× (scale bar = 50 µm).| Product Name | Anti-TGF beta1 antibody-poly-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | poly-HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | TGFB1 |
|---|---|
| Gene Synonyms | CED LAP DPD1 TGFB IBDIMDE TGFbeta TGF-beta1 |
| Gene Full Name | transforming growth factor beta 1 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016] |
| Molecular Weight(MW) | 44 kDa（Observed:53 kDa） |
| Cellular Localization | Extracellular region or secreted |
| SwissProt ID | P01137 |
|---|
WB
Western blot analysis using TGF beta1 antibody against Hela (1), A431 (2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using TGF beta1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using TGF beta1 antibody with DAB staining.
IHC
(E) At 24 h post-pneumococcal 19F infection, immunohistochemical staining with anti-TGF-β1 polyclonal antibody was utilized to detect expression of TGF-β1 in lung tissues. Lung sections were examined under light microscopy at magnification 200× (scale bar = 100 µm) and 400× (scale bar = 50 µm).| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide |
