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Anti-eIF2 alpha antibody-HRP

Catalog Number:OM641763-HRP
Human;Mouse;Rat
WB;IHC
OM641763-HRP
Discount Price
OM641763-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-eIF2 alpha antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EIF2S1
Gene Synonyms EIF2
EIF-2
EIF2A
EIF-2A
EIF-2alpha
Gene Full Name eukaryotic translation initiation factor 2 subunit alpha
Gene Summary The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Molecular Weight(MW) 36 kDa
Source Rabbit
Cellular Localization Cytoplasm
Database Links
SwissProt ID P05198
Application

WB

Western blot analysis using eIF2 alpha antibody against Hep G2 (1), 3T3-L1 (2) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissues using eIF2 alpha antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using eIF2 alpha antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using eIF2 alpha antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using eIF2 alpha antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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