WB
Western blot analysis using SREBP1 antibody against NIH3T3 (1), Jurkat (2) cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using SREBP1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using SREBP1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using SREBP1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using SREBP1 antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using SREBP1 antibody with DAB staining.| Product Name | Anti-SREBP1 antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | SREBF1 |
|---|---|
| Gene Synonyms | HMD IFAP2 SREBP1 bHLHd1 |
| Gene Full Name | sterol regulatory element binding transcription factor 1 |
| Gene Summary | This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017] |
| Molecular Weight(MW) | 122 kDa |
| Source | Rabbit |
| Cellular Localization | Nucleus and Endoplasmic reticulum membrane. Golgi apparatus membrane. |
| SwissProt ID | P36956 |
|---|
WB
Western blot analysis using SREBP1 antibody against NIH3T3 (1), Jurkat (2) cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human esophageal cancer tissues using SREBP1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using SREBP1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Kidney tissues using SREBP1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate tissues using SREBP1 antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using SREBP1 antibody with DAB staining.| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
