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Anti-F8 antibody-HRP

Catalog Number:OM641836-HRP
Human;Mouse;Rat
IHC
OM641836-HRP
Discount Price
OM641836-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-F8 antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol F8
Gene Synonyms AHF
F8B
F8C
HEMA
FVIII
DXS1253E
Gene Full Name coagulation factor VIII
Gene Summary This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
Source Rabbit
Cellular Localization Secreted
Database Links
SwissProt ID P00451
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cance tissues using F8 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human esphageal cance tissues using F8 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human liver cance tissues using F8 antibody with DAB staining.
Application Notes IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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