IHC
Immunohistochemistry of paraffin-embedded human placenta tissue using F8 Antibody at dilution of 1:100IHC
Immunohistochemistry of paraffin-embedded human kidney tissue using F8 Antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of Hela cells using F8 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-F8 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Coagulation factor VIII protein (1-216AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC |
| IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | F8 |
|---|---|
| Gene Synonyms | AHF F8B F8C HEMA FVIII THPH13 DXS1253E |
| Gene Full Name | coagulation factor VIII |
| Gene Summary | This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008] |
| Alternative Names | AHF antibody Antihemophilic factor antibody Coagulation factor VIII antibody coagulation factor VIII procoagulant component antibody coagulation factor VIIIc antibody DXS1253E antibody F8 antibody F8b antibody F8c antibody FA8_HUMAN antibody factor VIII F8B antibody Factor VIIIa light chain antibody FactorVIII antibody FVIII antibody Hema antibody Hemophilia A antibody Hemophilia classic antibody OTTHUMP00000061446 antibody OTTHUMP00000196174 antibody Procoagulant component antibody |
| Cellular Localization | Secreted, extracellular space. |
IHC
Immunohistochemistry of paraffin-embedded human placenta tissue using F8 Antibody at dilution of 1:100
IHC
Immunohistochemistry of paraffin-embedded human kidney tissue using F8 Antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of Hela cells using F8 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
