| Product Name | Anti-MSH6 antibody-DBCO |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinent Proteins |
| Conjugation | DBCO |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Mouse |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MSH6 |
|---|---|
| Gene Synonyms | GTBP HSAP p160 GTMBP HNPCC5 MMRCS3 |
| Gene Full Name | mutS homolog 6 |
| Gene Summary | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |
| Molecular Weight(MW) | 160 kDa |
| Source | Mouse |
| Cellular Localization | Chromosome, Nucleus |
| SwissProt ID | P52701 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
