| Product Name | Anti-Phospho-MSH6 (Ser14) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH |
| Modification | p-Ser14 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MSH6 |
|---|---|
| Gene Synonyms | GTBP HSAP p160 GTMBP MSH-6 HNPCC5 LYNCH5 MMRCS3 |
| Gene Full Name | mutS homolog 6 |
| Gene Summary | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |
| Alternative Names | DNA mismatch repair protein Msh6 G/T mismatch binding protein G/T mismatch-binding protein GTBP GTMBP hMSH6 HNPCC 5 HNPCC5 HSAP MSH 6 MSH6 MSH6_HUMAN mutS (E. coli) homolog 6 MutS alpha 160 kDa subunit MutS homolog 6 (E. coli) mutS homolog 6 MutS-alpha 160 kDa subunit p160 Sperm associated protein |
| Molecular Weight(MW) | 153 kDa |
| Cellular Localization | Nucleus, chromosome. |
| SwissProt ID | P52701 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
