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Anti-INSR antibody-poly-HRP

Catalog Number:OM642141-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642141-poly-HRP
Discount Price
OM642141-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-INSR antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol INSR
Gene Synonyms HHF5
CD220
Gene Full Name insulin receptor
Gene Summary This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Molecular Weight(MW) 156 kDa
Source Rabbit
Cellular Localization Cell membrane, Endosome, Lysosome, Membrane
Database Links
SwissProt ID P06213
Application

WB

Western blot analysis using INSR antibody against A549(1), Hela(2), A431(3), MCF-7(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using INSR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using INSR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney tissues using INSR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using INSR antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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