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Anti-Caldesmon antibody-HRP

Catalog Number:OM642243-HRP
Human;Mouse;Rat
WB;IHC
OM642243-HRP
Discount Price
OM642243-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-Caldesmon antibody-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CALD1
Gene Synonyms CDM
HCAD
LCAD
H-CAD
L-CAD
NAG22
Gene Full Name caldesmon 1
Gene Summary This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Molecular Weight(MW) 93 kDa
Cellular Localization Cytoplasm, Cytoskeleton
Database Links
SwissProt ID Q05682
Application

WB

Western blot analysis using Caldesmon antibody against A431(1), COS-7(2), MCF-7(3) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using Caldesmon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human kidney tissues using Caldesmon antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissues using Caldesmon antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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