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Anti-Phospho-Caldesmon (Ser789) antibody

Catalog Number:OM682135
OM682135
Discount Price
OM682135-100ul
100ul
Product Profile
Product Name Anti-Phospho-Caldesmon (Ser789) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser789
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CALD1
Gene Synonyms CDM
HCAD
LCAD
h-CD
H-CAD
L-CAD
NAG22
Gene Full Name caldesmon 1
Gene Summary This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Alternative Names CAD
CALD 1
CALD1
CALD1_HUMAN
Caldesmon 1
Caldesmon 1 Isoform 1
Caldesmon 1 Isoform 2
Caldesmon 1 Isoform 3
Caldesmon 1 Isoform 4
Caldesmon 1 Isoform 5
Caldesmon
Caldesmon1
CDM
H CAD
HCAD
L CAD
LCAD
MGC21352
NAG22
Molecular Weight(MW) 93 kDa
Cellular Localization Cytoplasm, Cytoskeleton.
Database Links
SwissProt ID Q05682
Application

ELISA

Coat the plate with 100ng immunizing antigen. The phospho-specific antibody,pbs only can specifically recognize phosphorylated peptide and enable quantitative detection over a wide dynamic range. Non-phosphorylated peptide shows no cross-reactivity, and the background signal remains low, indicating that the phospho-specific antibody,pbs only possesses high specificity and an excellent signal-to-noise ratio. Black line: phospho-peptide; Rad line: non-phospho peptide
Additional Information
Form Liquid
Storage Instructions Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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