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Anti-PKR antibody-poly-HRP

Catalog Number:OM642289-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642289-poly-HRP
Discount Price
OM642289-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-PKR antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol EIF2AK2
Gene Synonyms PKR
PRKR
DYT33
LEUDEN
EIF2AK1
PPP1R83
Gene Full Name eukaryotic translation initiation factor 2 alpha kinase 2
Gene Summary The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]
Molecular Weight(MW) 62 kDa
Cellular Localization Cytoplasm, Nucleus
Database Links
SwissProt ID P19525
Application

WB

Western blot analysis using PKR antibody against HUVEC(1), Hela(2), HEK293(3), K562(4) cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using PKR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using PKR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer 2 tissues using PKR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human thyroid carcinoma tissues using PKR antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human rectal cancer tissues using PKR antibody with DAB staining.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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