WB
Western blot analysis using P4HB antibody against PANC-1(1),COS7(2),MCF-7(3),NIH3T3(4)cell lysate.IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using P4HB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using P4HB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using P4HB antibody with DAB staining.IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using P4HB antibody with DAB staining.WB
Western blot analysis using P4HB antibody against Mouse intestine tissue(1),Mouse testes tissue(2),Mouse heart tissue(3),Mouse stomach tissue(4),Mouse liver tissue(5),Rat intestine tissue(6),Rat stomach tissue(7),Rat spleen tissue(8),Rat kidney tissue(9),Rat liver tissue(10) .| Product Name | Anti-P4HB antibody-HRP |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Polypeptide |
| Conjugation | HRP |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:200-1:2000 IHC:1:100-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | P4HB |
|---|---|
| Gene Synonyms | DSI GIT PDI PHDB PDIA1 PO4DB PO4HB PROHB CLCRP1 ERBA2L P4Hbeta |
| Gene Full Name | prolyl 4-hydroxylase subunit beta |
| Gene Summary | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. |
| Molecular Weight(MW) | 57 kDa |
| Cellular Localization | Cell membrane, Endoplasmic reticulum, Membrane |
| SwissProt ID | P07237 |
|---|
WB
Western blot analysis using P4HB antibody against PANC-1(1),COS7(2),MCF-7(3),NIH3T3(4)cell lysate.
IHC
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using P4HB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human Cervical cancer metastasis tissues using P4HB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human renal carcinoma tissues using P4HB antibody with DAB staining.
IHC
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using P4HB antibody with DAB staining.
WB
Western blot analysis using P4HB antibody against Mouse intestine tissue(1),Mouse testes tissue(2),Mouse heart tissue(3),Mouse stomach tissue(4),Mouse liver tissue(5),Rat intestine tissue(6),Rat stomach tissue(7),Rat spleen tissue(8),Rat kidney tissue(9),Rat liver tissue(10) .| Application Notes | WB:1:200-1:2000 IHC:1:100-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide. |
