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Anti-FLT3 antibody-poly-HRP

Catalog Number:OM642667-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642667-poly-HRP
Discount Price
OM642667-poly-HRP-100ul
1~2 Week
100ul
1~2 Week
Product Profile
Product Name Anti-FLT3 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FLT3
Gene Synonyms FLK2
STK1
CD135
FLK-2
Gene Full Name fms related receptor tyrosine kinase 3
Gene Summary This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
Molecular Weight(MW) 113KD
Cellular Localization Endoplasmic reticulum
Database Links
SwissProt ID P36888
Application

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using FLT3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human lung cancer tissues using FLT3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using FLT3 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human bladder cancer tissues using FLT3 antibody with DAB staining.

WB

Western blot analysis using FLT3 antibody against Mouse heart(1),Mouse stomach(2),Mouse liver(3),Rat intestine(4),Rat stomach(5),Rat spleen(6),Rat kidney(7),Rat serum(8),Mouse muscle(9) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide.
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