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Anti-STAT1 antibody-poly-HRP

Catalog Number:OM642828-poly-HRP
Human;Mouse;Rat
WB;IHC
OM642828-poly-HRP
Discount Price
OM642828-poly-HRP-100ul
100ul
Product Profile
Product Name Anti-STAT1 antibody-poly-HRP
Antibody Type Primary Antibodies
Immunogen Polypeptide
Conjugation poly-HRP
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WBIHC
WB:1:200-1:2000
IHC:1:100-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol STAT1
Gene Synonyms CANDF7
IMD31A
IMD31B
IMD31C
ISGF-3
STAT91
Gene Full Name signal transducer and activator of transcription 1
Gene Summary The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]
Molecular Weight(MW) 87kDa
Cellular Localization Cytoplasm. Nucleus
Database Links
SwissProt ID P42224
Application

WB

Western blot analysis using STAT1 antibody against Hela(1), Huvec(2), A431(3)cell lysate.

IHC

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissues using STAT1 antibody with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissues using STAT1 antibody with DAB staining.

WB

(B) DEF cells were transfected with a lentiviral vector expressing duck RIG-I and a lentivirus encoding ZsGreen for 24 h, and then infected with DEV at an MOI of 1 or mock-infected for 48 h, Expression levels of STAT1 and pSTAT1 in the cell lysates were analyzed by western blotting, with β-actin protein as the control.

WB

Western blot analysis using STAT1 antibody against Mouse brain(1),Mouse liver(2) tissue.
Application Notes WB:1:200-1:2000
IHC:1:100-1:1000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300.
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