| Product Name | Anti-Phospho-STAT1 (Ser727) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide conjugated with KLH. |
| Modification | p-Ser727 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | STAT1 |
|---|---|
| Gene Synonyms | CANDF7 IMD31A IMD31B IMD31C ISGF-3 STAT91 |
| Gene Full Name | signal transducer and activator of transcription 1 |
| Gene Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020] |
| Alternative Names | CANDF7 DKFZp686B04100 ISGF 3 ISGF3 OTTHUMP00000163552 OTTHUMP00000165046 OTTHUMP00000165047 OTTHUMP00000205845 Signal transducer and activator of transcription 1 Signal transducer and activator of transcription 1 91kDa Signal transducer and activator of transcription 1-alpha/beta Stat1 STAT1_HUMAN STAT91 Transcription factor ISGF-3 components p91/p84 |
| Molecular Weight(MW) | 87 kDa |
| Cellular Localization | Cytoplasm, Nucleus. |
| SwissProt ID | P42224 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Storage Buffer | Purified antibody in PBS with 0.05% sodium azide,40% Glycerol. |
