The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Molecular Weight(MW)
32kDa
Cellular Localization
Cell membrane; Multi-pass membrane protein
Application
WB
Western Blot analysis of HeLa cells using CD37 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000
IHC
Immunohistochemical analysis of paraffin-embedded human-liver, antibody was diluted at 1:100
Application Notes
WB:1:500-1:2000 IHC:1:100-1:300
Additional Information
Form
Liquid
Storage Instructions
-20℃
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.09% (W/V) sodium azide.