This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types. [provided by RefSeq, Aug 2017]
Alternative Names
FAT10 UBD-3 GABBR1 UBD Ubiquitin D
FAT10
Molecular Weight(MW)
18kDa(Observed MW: 23kDa)
Cellular Localization
Cytoplasm,Nucleus.
Application
WB
All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
ICC/IF
Immunofluorescent analysis using the Antibody at 1:50 dilution.
Application Notes
WB:1:1000-1:2000 IHC:1:100-1:200 ICC:1:50-1:200
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Storage Buffer
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.