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Histone H2A.Z (Acetyl K7) Rabbit Polyclonal Antibody

Catalog Number:OM643575
OM643575
Discount Price
OM643575-100ul
2~3 Week
100ul
OM643575-50ul
50ul
OM643575-20ul
20ul
2~3 Week
Product Profile
Product Name Histone H2A.Z (Acetyl K7) Rabbit Polyclonal Antibody
Antibody Type Primary Antibodies
Immunogen Synthetic Peptide of Histone H2A.Z (Acetyl Lys7)
Modification Acetyl K7
Key Feature
Clonality Monoclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol H2AZ1
Gene Synonyms H2AZ
H2A.z
H2A/z
H2AFZ
H2A.Z-1
Molecular Weight(MW) 14 kDa
Function Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Application

WB

Western blot analysis of extracts from Hela cells, untreated (-) or treated, 1:5000.Secondary antibodywas diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit.
Application Notes WB:1:500-1:1000
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
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