WB
Positive WB detected in: MCF-7 whole cell lysate, Mouse Liver tissue, Mouse Kidney tissue, All lanes: NRXN1 antibody at 1:2000, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.WB
Positive WB detected in: Mouse heart tissue, Mouse kidney tissue, All lanes: NRXN1 antibody at 2μg/ml, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.ICC/IF
Immunofluorescent analysis of HepG2 cells using NRXN1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-NRXN1 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Neurexin-1-beta protein (184-363AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| WB:1:1000-1:5000 ICC/IF:1:50-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NRXN1 |
|---|---|
| Gene Synonyms | PTHSL2 SCZD17 Hs.22998 |
| Gene Full Name | neurexin 1 |
| Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016] |
| Alternative Names | NRXN1 antibody Neurexin-1-beta antibody Neurexin I-beta antibody |
| Molecular Weight(MW) | 47 kDa |
| Cellular Localization | Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein. |
WB
Positive WB detected in: MCF-7 whole cell lysate, Mouse Liver tissue, Mouse Kidney tissue, All lanes: NRXN1 antibody at 1:2000, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.
WB
Positive WB detected in: Mouse heart tissue, Mouse kidney tissue, All lanes: NRXN1 antibody at 2μg/ml, Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.
ICC/IF
Immunofluorescent analysis of HepG2 cells using NRXN1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | WB:1:1000-1:5000 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
