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Rabbit anti-CCL2 Polyclonal antibody

Catalog Number:OM645170
OM645170
Discount Price
OM645170-100ul
100ul
OM645170-50ul
50ul
Product Profile
Product Name Rabbit anti-CCL2 Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Human C-C motif chemokine 2 protein (24-99AA)
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:500-1:2000
IHC:1:20-1:200
ICC/IF:1:50-1:200
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol CCL2
Gene Synonyms HC11
MCAF
MCP1
MCP-1
SCYA2
GDCF-2
SMC-CF
HSMCR30
Gene Full Name C-C motif chemokine ligand 2
Gene Summary This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]
Alternative Names C-C motif chemokine 2 antibody
CCL2 antibody
CCL2_HUMAN antibody
Chemokine (C C motif) ligand 2 antibody
GDCF 2 antibody
GDCF-2 antibody
GDCF2 antibody
HC11 antibody
HSMCR30 antibody
JE antibody
MCAF antibody
MCP 1 antibody
MCP-1 antibody
MCP1 antibody
MGC9434 antibody
Monocyte chemoattractant protein 1 antibody
Monocyte chemotactic and activating factor antibody
Monocyte chemotactic protein 1 antibody
Monocyte secretory protein JE antibody
SCYA2 antibody
Small inducible cytokine A2 (monocyte chemotactic protein 1
homologous to mouse Sig je) antibody
Small inducible cytokine A2 antibody
Small inducible cytokine subfamily A (Cys Cys)
member 2 antibody
Small-inducible cytokine A2 antibody
SMC CF antibody
SMC-CF antibody
SMCCF antibody
Molecular Weight(MW) 12 kDa(Observed band size: 50 kDa)
Cellular Localization Secreted.
Application

WB

All lanes: CCL2 antibody at 2µg/ml + EC109 whole cell lysate, Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution.

IHC

Immunohistochemistry of paraffin-embedded human liver cancer using CCL2 Antibody at dilution of 1:100.

IHC

Immunohistochemistry of paraffin-embedded human breast cancer using CCL2 Antibody at dilution of 1:100.

ICC/IF

Immunofluorescent analysis of Hela cells using CCL2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Application Notes WB:1:500-1:2000
IHC:1:20-1:200
ICC/IF:1:50-1:200
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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