WB
mouse spleen tissue were subjected to SDS PAGE followed by western blot with PATZ1 Antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.WB
Raji cells were subjected to SDS PAGE followed by western blot with PATZ1 Antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.| Product Name | PATZ1 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant human PATZ1 protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ChIPIHCWB |
| WB:1:500-1:2000 IHC:1:100-1:1000 IP:1:10-1:100 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | PATZ1 |
|---|---|
| Gene Synonyms | ZSG MAZR PATZ RIAZ ZBTB19 ZNF278 dJ400N23 |
| Gene Full Name | POZ/BTB and AT hook containing zinc finger 1 |
| Gene Summary | The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36.1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene. [provided by RefSeq, Jul 2008] |
| Alternative Names | MAZR PATZ POZ- AT hook- and zinc finger-containing protein 1 Protein kinase A RI subunit alpha-associated protein RIAZ |
| Molecular Weight(MW) | 70-74 kDa |
| Cellular Localization | Nucleus. |
WB
mouse spleen tissue were subjected to SDS PAGE followed by western blot with PATZ1 Antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.
WB
Raji cells were subjected to SDS PAGE followed by western blot with PATZ1 Antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.| Application Notes | WB:1:500-1:2000 IHC:1:100-1:1000 IP:1:10-1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C. Stable for one year after shipment. |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
