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Rabbit anti-AVP Polyclonal antibody

Catalog Number:OM645272
OM645272
Discount Price
OM645272-100ul
100ul
Product Profile
Product Name Rabbit anti-AVP Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Human Vasopressin-neurophysin 2-copeptin protein (126-164AA)
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCWB
WB:1:500-1:2000
IHC:1:20-1:200
Species Reactivity HumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol AVP
Gene Synonyms VP
ADH
ARVP
AVRP
AVP-NPII
Gene Full Name arginine vasopressin
Gene Summary This gene encodes a member of the vasopressin/oxytocin family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the neuropeptide hormone arginine vasopressin, and two other peptides, neurophysin 2 and copeptin. Arginine vasopressin is a posterior pituitary hormone that is synthesized in the supraoptic nucleus and paraventricular nucleus of the hypothalamus. Along with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis where it is either stored or secreted into the bloodstream. The precursor is thought to be activated while it is being transported along the axon to the posterior pituitary. Arginine vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney, and also causes vasoconstriction of the peripheral vessels. This hormone can contract smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in this gene cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI). This gene is present in a gene cluster with the related gene oxytocin on chromosome 20. [provided by RefSeq, Nov 2015]
Alternative Names AVP antibody
ARVP antibody
VPVasopressin-neurophysin 2-copeptin antibody
AVP-NPII) [Cleaved into: Arg-vasopressin antibody
Arginine-vasopressin)
Neurophysin 2 antibody
Neurophysin-II)
Copeptin] antibody
Molecular Weight(MW) 18 kDa
Cellular Localization Secreted.
Application

WB

All lanes: AVP antibody at 2µg/ml + Rat gonadal tissue, Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution.

IHC

Immunohistochemistry of paraffin-embedded human breast cancer using AVP Antibody at dilution of 1:100.
Application Notes WB:1:500-1:2000
IHC:1:20-1:200
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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