WB
Positive WB detected in: PC-3 whole cell lysate, All lanes: HRH1 antibody at 2.8μg/ml. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.IHC
Immunohistochemistry of paraffin-embedded human small intestine tissue using HRH1 Antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of HepG2 cells using HRH1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-HRH1 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human Histamine H1 receptor protein (211-416AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| WB:1:200-1:5000 IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HRH1 |
|---|---|
| Gene Synonyms | H1R H1-R HH1R hisH1 |
| Gene Full Name | histamine receptor H1 |
| Gene Summary | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. The protein encoded by this gene is an integral membrane protein and belongs to the G protein-coupled receptor superfamily. It mediates the contraction of smooth muscles, the increase in capillary permeability due to contraction of terminal venules, the release of catecholamine from adrenal medulla, and neurotransmission in the central nervous system. It has been associated with multiple processes, including memory and learning, circadian rhythm, and thermoregulation. It is also known to contribute to the pathophysiology of allergic diseases such as atopic dermatitis, asthma, anaphylaxis and allergic rhinitis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2015] |
| Alternative Names | BPHS mouse homolog of antibody H1 R antibody H1R antibody HH1R antibody HisH1 antibody Histamine H(1) receptor antibody Histamine H1 receptor antibody Histamine receptor H1 antibody Histamine receptor subclass H1 antibody Hrh1 antibody HRH1_HUMAN antibody |
| Molecular Weight(MW) | 56 kDa |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
WB
Positive WB detected in: PC-3 whole cell lysate, All lanes: HRH1 antibody at 2.8μg/ml. Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human small intestine tissue using HRH1 Antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of HepG2 cells using HRH1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | WB:1:200-1:5000 IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
