IHC
Immunohistochemistry of paraffin-embedded human brain tissue using Rabbit anti-PRDM16 Polyclonal antibody at dilution of 1:100.ICC/IF
Immunofluorescent analysis of PC-3 cells using Rabbit anti-PRDM16 Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Product Name | Rabbit anti-PRDM16 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human PR domain zinc finger protein 16 protein (448-683AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC |
| IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | PRDM16 |
|---|---|
| Gene Synonyms | MEL1 KMT8F LVNC8 PFM13 CMD1LL |
| Gene Full Name | PR/SET domain 16 |
| Gene Summary | The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Alternative Names | CMD1LL antibody KIAA1675 antibody LVNC8 antibody MDS1/EVI1 like gene 1 antibody MDS1/EVI1-like gene 1 antibody MEL1 antibody PFM 13 antibody PFM13 antibody PR domain containing 16 antibody PR domain containing protein 16 antibody PR domain zinc finger protein 16 antibody PR domain-containing protein 16 antibody PRD16_HUMAN antibody Prdm16 antibody Transcription factor MEL 1 antibody Transcription factor MEL1 antibody |
| Cellular Localization | Nucleus. Cytoplasm. |
IHC
Immunohistochemistry of paraffin-embedded human brain tissue using Rabbit anti-PRDM16 Polyclonal antibody at dilution of 1:100.
ICC/IF
Immunofluorescent analysis of PC-3 cells using Rabbit anti-PRDM16 Polyclonal antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).| Application Notes | IHC:1:20-1:200 ICC/IF:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
