WB
All lanes: FYCO1 antibody at 2.5µg/ml, Lane 1: HepG2 whole cell lysate, Lane 2: Mouse liver tissue, Secondary, Goat polyclonal to rabbit IgG at 1/10000 dilution.IHC
Immunohistochemistry of paraffin-embedded human thyroid tissue using FYCO1 Antibody at dilution of 1:100| Product Name | Rabbit anti-FYCO1 Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Recombinant Human FYVE and coiled-coil domain-containing protein 1 protein (2-255AA) |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:20-1:200 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FYCO1 |
|---|---|
| Gene Synonyms | CATC2 RUFY3 ZFYVE7 CTRCT18 |
| Gene Full Name | FYVE and coiled-coil domain autophagy adaptor 1 |
| Gene Summary | The gene encodes a Rab7 adapter protein that is implicated in the microtubule transport of autophagosomes. The encoded protein contains a RUN domain, a FYVE-type zinc finger domain, and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P), the autophagosome marker LC3, and the kinesin KIF5. Mutations in this gene are associated with inclusion body myositis (IBM) and autosomal recessive congenital cataracts (CATC2). [provided by RefSeq, Aug 2020] |
| Alternative Names | CATC2 antibody CTRCT18 antibody DKFZp779K1152 antibody FLJ13335 antibody FYCO1 antibody FYCO1_HUMAN antibody FYVE and coiled coil domain containing 1 antibody FYVE and coiled coil domain containing protein 1 antibody FYVE and coiled-coil domain-containing protein 1 antibody MGC126517 antibody MGC126519 antibody RUFY3 antibody RUN and FYVE domain containing 3 antibody ZFYVE7 antibody Zinc finger FYVE domain containing protein 7 antibody Zinc finger FYVE domain-containing protein 7 antibody |
| Molecular Weight(MW) | 167 kDa |
| Cellular Localization | Cytoplasmic vesicle, autophagosome. Endosome. Lysosome. Note=Localizes to the external but not to the internal membrane of autophagosomes, and upon autophagosome/late endosome/lysosome fusion, it stays on the external surface of autolysosomes. |
WB
All lanes: FYCO1 antibody at 2.5µg/ml, Lane 1: HepG2 whole cell lysate, Lane 2: Mouse liver tissue, Secondary, Goat polyclonal to rabbit IgG at 1/10000 dilution.
IHC
Immunohistochemistry of paraffin-embedded human thyroid tissue using FYCO1 Antibody at dilution of 1:100| Application Notes | WB:1:500-1:2000 IHC:1:20-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
