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DFNA5/GSDME Rabbit mAb

Catalog Number:OM645810
OM645810
Discount Price
OM645810-100ul
100ul
OM645810-50ul
50ul
Product Profile
Product Name DFNA5/GSDME Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications WB
WB:1:2000-1:10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol GSDME
Gene Synonyms DFNA5
ICERE-1
Gene Full Name gasdermin E
Gene Summary Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names DFNA5
ICERE1
Non-syndromic hearing impairment protein 5
Inversely correlated with estrogen receptor expression 1
ICERE-1
Molecular Weight(MW) 36 kDa,55 kDa(Observed band size: 55 kDa)
Cellular Localization Membrane , Cytoplasm
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-DFNA5/GSDME antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
Application Notes WB:1:2000-1:10000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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