Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-DFNA5/GSDME antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality
Monoclonal
Isotype
IgG,K
Host Species
Rabbit
Tested Applications
WB
WB:1:2000-1:10000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Protein A
Target Information
Gene Symbol
GSDME
Gene Synonyms
DFNA5 ICERE-1
Gene Full Name
gasdermin E
Gene Summary
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
DFNA5 ICERE1 Non-syndromic hearing impairment protein 5 Inversely correlated with estrogen receptor expression 1 ICERE-1
Molecular Weight(MW)
36 kDa,55 kDa(Observed band size: 55 kDa)
Cellular Localization
Membrane , Cytoplasm
Application
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-DFNA5/GSDME antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.