Recombinant Bovine respiratory syncytial virus Nucleoprotein protein (1-391AA)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:1000-1:5000
Species Reactivity
Virus
Concentration
1mg/ml
Purification
Protein G
Target Information
Gene Symbol
N
Alternative Names
N antibody Nucleoprotein antibody Protein N antibody Nucleocapsid protein antibody
Molecular Weight(MW)
59 kDa
Function
Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway. May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs.
Cellular Localization
Virion. Host cytoplasm.
Application
WB
Western Blot,Positive WB detected in Recombinant protein
All lanes: N antibody at 1:2000.Secondary,Goat polyclonal to rabbit IgG at 1/50000 dilution.
Application Notes
WB:1:1000-1:5000
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.