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Rabbit anti-N Polyclonal antibody

Catalog Number:OM645825
OM645825
Discount Price
OM645825-100ul
100ul
Product Profile
Product Name Rabbit anti-N Polyclonal antibody
Antibody Type Primary Antibodies
Immunogen Recombinant Bovine respiratory syncytial virus Nucleoprotein protein (1-391AA)
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:1000-1:5000
Species Reactivity Virus
Concentration 1mg/ml
Purification Protein G
Target Information
Gene Symbol N
Alternative Names N antibody
Nucleoprotein antibody
Protein N antibody
Nucleocapsid protein antibody
Molecular Weight(MW) 59 kDa
Function Encapsidates the viral RNA genome by forming a left-handed helical nucleocapsid that protects the RNA from nucleases. RNA replication depends on the availability of soluble nucleoprotein. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Together with the phosphoprotein, sequesters host NF-kappa-B in inclusion bodies (IBs) thereby inhibiting this host defense pathway. May also act as a modulator of the innate immune response by sequestration of host IFIH1/MDA5 and MAVS into IBs.
Cellular Localization Virion. Host cytoplasm.
Application

WB

Western Blot,Positive WB detected in Recombinant protein All lanes: N antibody at 1:2000.Secondary,Goat polyclonal to rabbit IgG at 1/50000 dilution.
Application Notes WB:1:1000-1:5000
Additional Information
Form Liquid
Storage Instructions Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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