Recombinant AGC (Glu588~Arg684 (Accession # P07897)) expressed in E.coli
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:0.01-2µg/mL
Species Reactivity
Rat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
Acan
Gene Synonyms
Agc Agc1
Gene Full Name
aggrecan
Gene Summary
Enables calcium ion binding activity. Involved in several processes, including chondroblast differentiation; response to acidic pH; and response to glucose. Located in extracellular space; neuronal cell body; and perineuronal net. Used to study degenerative disc disease. Biomarker of congestive heart failure; degenerative disc disease; osteoarthritis; and status epilepticus. Human ortholog(s) of this gene implicated in spondyloepiphyseal dysplasia Kimberley type. Orthologous to human ACAN (aggrecan). [provided by Alliance of Genome Resources, Jul 2025]
Alternative Names
ACAN AGC1 AGCAN CSPG1 CSPCP CSPGCP MSK16 SEDK Cartilage-specific proteoglycan core protein Large Aggregating Proteoglycan Chondroitin Sulfate Proteoglycan 1