WB
Western blot analysis of lysates from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right is blocked with the phospho peptide.IHC
Immunohistochemistry analysis of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The picture on the right is blocked with the phospho peptide.| Product Name | GluR4 (Phospho Ser862) Rabbit pAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GluR4 around the phosphorylation site of Ser862. AA range:828-877 |
| Modification | p-Ser862 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIA4 |
|---|---|
| Gene Synonyms | GLUR4 GLURD GluA4 GLUR4C NEDSGA GluA4-ATD |
| Gene Full Name | glutamate ionotropic receptor AMPA type subunit 4 |
| Gene Summary | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008] |
| Alternative Names | GRIA4 GLUR4 Glutamate receptor 4 GluR-4 GluR4 AMPA-selective glutamate receptor 4 GluR-D Glutamate receptor ionotropic AMPA 4 GluA4 |
| Molecular Weight(MW) | 100 kDa |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein. Cell projection , dendrite. Interaction with CNIH2 , CNIH3 and PRKCG promotes cell surface expression. |
WB
Western blot analysis of lysates from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right is blocked with the phospho peptide.
IHC
Immunohistochemistry analysis of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The picture on the right is blocked with the phospho peptide.| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
