WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-p38 MAPK (Phospho Thr180/Tyr182) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.IHC
Human kidney was stained with anti-p38 MAPK (Phospho Thr180/Tyr182) Rabbit antibody.| Product Name | p38 MAPK (Phospho Thr180/Tyr182) Rabbit mAb |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Modification | p-Thr180/Tyr182 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG,K |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:2000-1:10000 IHC:1:200-1:1000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | MAPK14 |
|---|---|
| Gene Synonyms | RK p38 CSBP EXIP Mxi2 CSBP1 CSBP2 CSPB1 PRKM14 PRKM15 SAPK2A p38ALPHA |
| Gene Full Name | mitogen-activated protein kinase 14 |
| Gene Summary | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] |
| Alternative Names | Mitogen-activated protein kinase 14 MAP kinase 14 MAPK 14 Cytokine suppressive anti-inflammatory drug-binding protein CSAID-binding protein CSBP MAP kinase MXI2 MAX-interacting protein 2 Mitogen-activated protein kinase p38 alpha MAP kinase p38 alpha Stress-activated protein kinase 2a SAPK2a MAP kinase 12 MAPK 12 Extracellular signal-regulated kinase 6 ERK-6 Mitogen-activated protein kinase p38 gamma MAP kinase p38 gamma Stress-activated protein kinase 3 MAP kinase 13 MAPK 13 Mitogen-activated protein kinase p38 delta MAP kinase p38 delta Stress-activated protein kinase 4 MAPK11 PRKM11 SAPK2 SAPK2B Mitogen-activated protein kinase 11 MAP kinase 11 MAPK 11 Mitogen-activated protein kinase p38 beta MAP kinase p38 beta p38b Stress-activated protein kinase 2b SAPK2b p38-2 |
| Molecular Weight(MW) | 44 kDa |
| Cellular Localization | Cytoplasm , Nucleus. |
WB
Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-p38 MAPK (Phospho Thr180/Tyr182) antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.
IHC
Human kidney was stained with anti-p38 MAPK (Phospho Thr180/Tyr182) Rabbit antibody.| Application Notes | WB:1:2000-1:10000 IHC:1:200-1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
