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SREBP-2 Rabbit mAb

Catalog Number:OM645949
OM645949
Discount Price
OM645949-100ul
100ul
OM645949-50ul
50ul
Product Profile
Product Name SREBP-2 Rabbit mAb
Antibody Type Primary Antibodies
Immunogen Synthesized peptide derived from human N-ternal SREBP 2.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications IHCWB
WB:1:2000-1:10000
IHC:1:200-1:1000
Species Reactivity HumanRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol SREBF2
Gene Synonyms SREBP2
bHLHd2
SREBP-2
Gene Full Name sterol regulatory element binding transcription factor 2
Gene Summary This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Alternative Names SRBP2
Sterol regulatory element-binding protein 2
SREBP-2
Class D basic helix-loop-helix protein 2
bHLHd2
Sterol regulatory element-binding transcription factor 2
[Cleaved into: Processed sterol regulatory element-binding protein 2]
Molecular Weight(MW) 124 kDa(Observed band size: 130 kDa)
Cellular Localization Endoplasmic reticulum membrane,Golgi apparatus membrane,Cytoplasmic vesicle, COPII-coated vesicle membrane.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-SREBP-2 antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody. Lane 1: HUVEC Lane 2: HepG2, Lane 2: Rat spleen .

IHC

Human tonsil was stained with anti-SREBP-2 Rabbit antibody.
Application Notes WB:1:2000-1:10000
IHC:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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