WB
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: ATP7A Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutesIHC
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using ATP7A Antibody at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)IHC
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ATP7A Antibody at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)| Product Name | Rabbit anti-ATP7A Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Synthetic peptide of Human ATP7A |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB:1:200-1:1000 IHC:1:50-1:200 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ATP7A |
|---|---|
| Gene Synonyms | MK MNK HMNX DSMAX SMAX3 |
| Gene Full Name | ATPase copper transporting alpha |
| Gene Summary | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013] |
| Alternative Names | ATP 7A antibody ATP7A antibody ATP7A_HUMAN antibody ATPase copper transporting alpha polypeptide antibody ATPase Cu++ transporting alpha polypeptide (Menkes syndrome) antibody ATPase Cu++ transporting alpha polypeptide antibody Copper pump 1 antibody Copper transporting ATPase 1 antibody Copper-transporting ATPase 1 antibody Cu++ transporting P type ATPase antibody DSMAX antibody FLJ17790 antibody MC 1 antibody MC1 antibody Menkes disease associated protein antibody Menkes disease-associated protein antibody Menkes syndrome antibody MK antibody MNK antibody OHS antibody OTTHUMP00000062077 antibody SMAX3 antibody |
| Cellular Localization | Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Melanosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendrite. Cell junction, synapse, postsynaptic density.; [Isoform 3]: Cytoplasm, cytosol.; [Isoform 5]: Endoplasmic reticulum. |
WB
Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: ATP7A Antibody at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using ATP7A Antibody at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ATP7A Antibody at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)| Application Notes | WB:1:200-1:1000 IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
