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Cathepsin D Rabbit mAb

Catalog Number:OM646189
OM646189
Discount Price
OM646189-100ul
100ul
OM646189-50ul
50ul
Product Profile
Product Name Cathepsin D Rabbit mAb
Antibody Type Primary Antibodies
Immunogen The specific immunogen used to produce this antibody is proprietary information.
Key Feature
Clonality Monoclonal
Isotype IgG,K
Host Species Rabbit
Tested Applications ICC/IFIHCWB
WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol CTSD
Gene Synonyms CPSD
CLN10
HEL-S-130P
Gene Full Name cathepsin D
Gene Summary This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Alternative Names CTSD
CPSD
Cathepsin D
Molecular Weight(MW) 44 kDa
Cellular Localization Secreted.
Application

WB

Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Cathepsin D antibody. The HRP-conjugated Goat anti-Rabbit IgG (H + L) antibody was used to detect the antibody.

IHC

Rat liver was stained with anti-Cathepsin D rabbit antibody.

IHC

Mouse liver was stained with anti-Cathepsin D rabbit antibody.

IHC

Human prostate was stained with anti-Cathepsin D rabbit antibody.

ICC/IF

Immunofluorescence analysis of HEK293. Picture A: Cathepsin D antibody (red). Picture B: DAPI (blue). Picture C: Merge of A+B.
Application Notes WB:1:1000-1:5000
IHC:1:200-1:1000
ICC/IF:1:200-1:1000
Additional Information
Form Liquid
Storage Instructions -15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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