The antiserum was produced against synthesized peptide derived from human ASCL1. AA range:109-158
Modification
Unmodified
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB:1:500-1:2000 IHC: 1:100-1:300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Symbol
ASCL1
Gene Synonyms
ASH1 HASH1 MASH1 bHLHa46
Gene Full Name
achaete-scute family bHLH transcription factor 1
Gene Summary
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
Alternative Names
ASCL1 ASH1 BHLHA46 HASH1 Achaete-scute homolog 1 ASH-1 hASH1 Class A basic helix-loop-helix protein 46 bHLHa46
Molecular Weight(MW)
25 kDa
Cellular Localization
Nucleus .
Application
WB
Western blot analysis of lysate from Jurkat cells, using ASCL1 antibody.
IHC
Immunohistochemistry analysis of ASCL1 antibody in paraffin-embedded human brain tissue.
Application Notes
WB:1:500-1:2000 IHC: 1:100-1:300
Additional Information
Form
Liquid
Storage Instructions
-15°C to -25°C/1 year(Do not lower than -25°C)
Storage Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.